Data Features

Highlights of new data, tools and resources on the Cancer Complexity Knowledge Portal

📈New Dataset: Impact of post-lysis stopping point prior to reverse transcription

By |2026-03-11T17:00:52+00:00March 11, 2026|CCKP, Data Features, Resources|

We’re excited to share the dataset “Impact of Post-Lysis Stopping Point Prior to Reverse Transcription,” generated using the newly developed particle-templated instant partition sequencing [...]

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🧰CCKP Toolkit Tool Feature: AMICI

By |2026-02-13T17:35:12+00:00February 25, 2026|Data Features|

AMICI (Advanced Multilanguage Interface for CVODES and IDAS) is a high-performance Python and C++ interface for solving large-scale ordinary and algebraic differential equation models. It provides [...]

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📈New Dataset: NR2F1 underlies persistence of residual disease in BRAF-mutant melanoma

By |2026-01-15T21:39:21+00:00January 15, 2026|CCKP, Data Features|

Targeted therapies for melanoma, like BRAF and MEK inhibitors, can shrink tumors but often fail to completely eliminate all cancer cells. A small group [...]

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📈New Dataset: Pancreatic cancer xenograft tumor RNA sequencing and pathologic differentiation of matched human tumors

By |2025-12-08T17:46:48+00:00September 25, 2025|CCKP, Data Features|

From Brown et al. (https://pubmed.ncbi.nlm.nih.gov/38471099/), this dataset investigates the epithelial to mesenchymal transition (EMT) in pancreatic cancer. EMT is believed to correlate with metastatic [...]

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New Dataset: Window of opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma

By |2025-07-09T16:41:54+00:00July 23, 2025|CCKP, Data Features|

This dataset investigates the effectiveness of p53 reactivation in treating glioblastoma. They achieve this by treating multiple patients with differing levels of MDM2 inhibitor [...]

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Featured Dataset: Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs

By |2024-10-02T21:22:27+00:00October 2, 2024|CCKP, Data Features|

Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs This study highlights the RNA sequencing and whole exome sequencing data associated with the investigation of a [...]

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NEW! Patient Advocacy Resources Available on the Cancer Complexity Knowledge Portal

By |2024-10-02T21:00:33+00:00October 2, 2024|CCKP, Community News, Data Features|

Patient advocates bring essential perspectives to cancer research and are involved in several consortia associated with the MC2 Center. To support their efforts, as [...]

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Featured Dataset: Spatial transcriptomics of xenograft tumor tissues

By |2024-07-11T14:35:46+00:00July 10, 2024|CCKP, Data Features|

This study aims to compare the epigenomes of different patient-derived models of colorectal cancer (PDO (Patient-Derived Organoid), PDX (Patient-Derived Xenograft), and PDOX (Patient-Derived Orthotopic [...]

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