Highlights of new data, tools and resources on the Cancer Complexity Knowledge Portal
Screening and treating early breast lesions (DCIS) hasn't done much to lower breast cancer deaths, a sign that some tumors are already headed down [...]
Pancreatic cancer kills about 90% of patients, mostly because it spreads to other organs. This dataset helps explain how. Researchers found that aggressive pancreatic [...]
More than 10 million cancer mutations in TCGA have no known functional effect. Rather than characterizing each one experimentally, this dataset uses transcription factor [...]
One of the persistent problems in AML is that leukemia cells don't all die from chemotherapy; some survive, go quiet, and eventually drive relapse. [...]
Immune cells called macrophages make up a large chunk of a glioblastoma tumor — and they help it grow, hide from treatment, and resist [...]
Bone metastasis is common across cancer types, but what's happening at the cellular level inside those lesions has been hard to map. This dataset uses [...]
A new single-cell RNA-sequencing dataset provides in-depth profiling of estrogen receptor (ER)-positive primary and metastatic breast cancer tumors from 23 patients, offering insight into [...]
We’re excited to share the dataset “Impact of Post-Lysis Stopping Point Prior to Reverse Transcription,” generated using the newly developed particle-templated instant partition sequencing [...]
AMICI (Advanced Multilanguage Interface for CVODES and IDAS) is a high-performance Python and C++ interface for solving large-scale ordinary and algebraic differential equation models. It provides [...]
Targeted therapies for melanoma, like BRAF and MEK inhibitors, can shrink tumors but often fail to completely eliminate all cancer cells. A small group [...]