📈New Dataset: NR2F1 underlies persistence of residual disease in BRAF-mutant melanoma
Targeted therapies for melanoma, like BRAF and MEK inhibitors, can shrink tumors but often fail to completely eliminate all cancer cells. A small group [...]
New Dataset: Window of opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma
This dataset investigates the effectiveness of p53 reactivation in treating glioblastoma. They achieve this by treating multiple patients with differing levels of MDM2 inhibitor [...]
Featured Dataset: Spatial transcriptomics of xenograft tumor tissues
This study aims to compare the epigenomes of different patient-derived models of colorectal cancer (PDO (Patient-Derived Organoid), PDX (Patient-Derived Xenograft), and PDOX (Patient-Derived Orthotopic [...]
Featured Dataset: Transcriptional dysregulation of BAHCC1 in melanoma [Cut & Tag]
Cut&Tag sequencing data from melanoma cells revealed that BAHCC1, a gene associated with Super-Enhancers (SE) and critical for cancer growth, is highly active compared [...]