Myeloid-derived suppressor cells (MDSCs) help tumors dodge the immune system, but they're hard to target: inside a tumor, they look almost identical to mature, [...]
Stargardt disease is the most common inherited cause of macular degeneration, but patients who lose the same gene, ABCA4, don't all lose their vision [...]
Screening and treating early breast lesions (DCIS) hasn't done much to lower breast cancer deaths, a sign that some tumors are already headed down [...]
dynamo-release answers a hard question in single-cell cancer biology: not just what state a cell is in, but where it's headed. This open-source Python [...]
More than 10 million cancer mutations in TCGA have no known functional effect. Rather than characterizing each one experimentally, this dataset uses transcription factor [...]
Cumulus helps researchers tackle one of single-cell genomics' biggest challenges: analyzing datasets too large for a laptop. It's a cloud-based framework for large-scale scRNA-seq and [...]
A new single-cell RNA-sequencing dataset provides in-depth profiling of estrogen receptor (ER)-positive primary and metastatic breast cancer tumors from 23 patients, offering insight into [...]
We’re excited to share the dataset “Impact of Post-Lysis Stopping Point Prior to Reverse Transcription,” generated using the newly developed particle-templated instant partition sequencing [...]